Clinical features and pharmacotherapy of bipolar disorder

Objective To explore the clinical features and pharmacotherapy of outpatients with bipolar disorder.Methods Outpatients with bipolar disorder according to DSM-IV were included and were assessed with self-made questionnaires.Results ① Two hundred and three cases of patients were enrolled.Among which 163 cases(80.3%)were diagnosed as bipolar disorder Ⅰ and 40 cases(19.7%)bipolar disorder Ⅱ.② The most important medicine was mood-stabilizations(70.4%)and the second antipsychotic(63%).③ More cases with bipolar disorder Ⅰ were treated with mood-stabilizations,antipsychotic and benzodiazepines than ones with bipolar disorder Ⅱ.While more cases with bipolar disorder Ⅱ were treated with antidepressants than ones with bipolar disorder Ⅰ were.④ 72.4% patients were receiving two or more than two kinds of drugs.⑤80.5% bipolar disorder patients were in stable condition.Conclusion There were more outpatients with bipolar disorder Ⅰ than ones with bipolar disorder Ⅱ.Patients with bipolar disorder Ⅱ were easy to be missed.The present medications have been already accommodated with the guidelines of pharmacotherapy in bipolar disorder both in China and abroad.Many patients were receiving more than one drug.Most patients received good effects.