人参
缺血
心肌缺血
药理学
化学
人参皂甙
五加科
心脏病学
医学
传统医学
病理
替代医学
作者
Jiazhen Wang,Huiyun Wang,Xiaodong Mou,Ming-Zhu Luan,Xiaofan Zhang,Xiuting He,Fenglan Zhao,Qingguo Meng
出处
期刊:Mini-reviews in Medicinal Chemistry
[Bentham Science]
日期:2020-11-10
卷期号:20 (16): 1610-1618
被引量:18
标识
DOI:10.2174/1389557520666200619115444
摘要
Ginseng is a traditional medicine with a complex chemical composition, wide bioactivity and unique pharmacological action. Many studies have confirmed that ginsenosides are the active ingredients of ginseng, and ginsenosides have always been the focus of different researchers. With the development of modern separation and analysis technology, more than 150 kinds of ginsenosides have been isolated. The ginsenosides Rb1, Rb2, Rc, Rg1 and Re account for more than 80% of total ginsenosides, and other saponins, such as Rd, Rg3 and Rh2, which are minor constituents, accounting for only a small portion of the total amount. In recent years, ginsenosides have been found to possess strong pharmacological activities, such as antioxidation, clearing of oxygen free radicals, reducing calcium overload and anti-apoptosis. Ginsenosides play a protective role in ischemia-reperfusion injury. This paper reviews the protective effects of ginsenosides on myocardial ischemia and ischemiareperfusion injury.
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