Efficient Synthesis of Molecular Precursors for Para‐Hydrogen‐Induced Polarization of Ethyl Acetate‐1‐ ¹³ C and Beyond

Labels of the reconstruction: The production of vinylated carboxylic compounds with a 13C isotopic label in the C1 position enables the synthesis of vinyl acetate-1-13C, a precursor for preparation of 13C NMR hyperpolarized ethyl acetate-1-13C. 13C hyperpolarization of about 1.8 % is achieved using para-hydrogen-induced polarization side arm hydrogenation (PHIP-SAH) suggesting potential for medical imaging.