中心性
人类免疫缺陷病毒(HIV)
亲密度
医学
混乱
认知
临床心理学
人口学
心理学
精神科
免疫学
数学分析
数学
社会学
精神分析
组合数学
作者
Zheng Zhu,Huan Wen,Zhaoxia Yang,Shuyu Han,Yanfen Fu,Lin Zhang,Yan Hu,Bei Wu
标识
DOI:10.1016/j.ijid.2021.05.084
摘要
ObjectivesTo explore and visualize the relationships among multiple symptoms in people living with HIV (PLWH) and compare centrality indices and the density of symptom networks among groups of individuals with different HIV-positive durations.MethodsWe conducted a secondary analysis of data from the HIV-related Symptoms Monitoring Survey conducted in China. Networks were constructed among 27 symptoms. Centrality properties, including strength and closeness, and network density were used to describe relationships among symptoms in 5 different HIV-positive duration groups.ResultsThe findings showed that PLWH with longer HIV-positive durations did not have more severe symptoms; instead, their symptom networks were denser than those of their newly HIV-diagnosed counterparts (F = 27.073, P < 0.001). Fatigue was the most severe and central symptom in PLWH with an HIV-positive duration <10 years (rS = 7.79–10.09, rB = 18–44, rC = 0.01). Confusion was the most central symptom across the 3 centrality indices (rS = 11.81, rB = 14.00, rC = 0.02) in PLWH who had HIV-positive durations >10 years.ConclusionThis study demonstrates a need to include an assessment of PLWH symptom networks as an essential component of HIV care. We recommended evaluating cognitive function and cognitive training as essential components of HIV care for long-term survivors, even in younger populations (aged ≤50 years).
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