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LettersApril 2021Acute Cardiovascular Events Associated With Influenza in Hospitalized AdultsShauna L. Newton, MD, James Song-Jeng Yeh, MD, MPHShauna L. Newton, MDMassachusetts General Hospital, Boston, MassachusettsSearch for more papers by this author, James Song-Jeng Yeh, MD, MPHMassachusetts General Hospital and Harvard Medical School, Boston, MassachusettsSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/L21-0016 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR: Chow and colleagues' article (1) strongly supports the known association between influenza infection and acute cardiovascular events. It then goes 1 step further by detailing the spectrum and prevalence of such events, with acute heart failure (aHF) and acute ischemic heart disease (IHD) being the most common. Of note, nearly half of the 9046 patients who had an acute cardiovascular event were diagnosed with acute IHD. Because heart disease remains the leading cause of death in the United States, identifying these types of associations is imperative.The article's Methods section describes how acute cardiovascular events were identified ...References1. Chow EJ, Rolfes MA, O’Halloran A, et al. Acute cardiovascular events associated with influenza in hospitalized adults. A cross-sectional study. Ann Intern Med. 2020;173:605-13. [PMID: 32833488]. doi: 10.7326/M20-1509 LinkGoogle Scholar2. Armstrong PW, Fu Y, Chang WC, et al. Acute coronary syndromes in the GUSTO-IIb trial: prognostic insights and impact of recurrent ischemia. The GUSTO-IIb Investigators. Circulation. 1998;98:1860-8. [PMID: 9799205] CrossrefMedlineGoogle Scholar3. DeFilippis AP, Chapman AR, Mills NL, et al. Assessment and treatment of patients with type 2 myocardial infarction and acute nonischemic myocardial injury. Circulation. 2019;140:1661-78. [PMID: 31416350] doi: 10.1161/CIRCULATIONAHA.119.040631 CrossrefMedlineGoogle Scholar4. Clar C, Oseni Z, Flowers N, et al. Influenza vaccines for preventing cardiovascular disease. Cochrane Database Syst Rev. 2015:CD005050. [PMID: 25940444] doi: 10.1002/14651858.CD005050.pub3 MedlineGoogle Scholar5. Udell JA, Zawi R, Bhatt DL, et al. Association between influenza vaccination and cardiovascular outcomes in high-risk patients: a meta-analysis. JAMA. 2013;310:1711-20. [PMID: 24150467] doi: 10.1001/jama.2013.279206 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Massachusetts General Hospital, Boston, MassachusettsMassachusetts General Hospital and Harvard Medical School, Boston, MassachusettsDisclosures: Authors have reported no disclosures of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L21-0016. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoAcute Cardiovascular Events Associated With Influenza in Hospitalized Adults Eric J. Chow , Melissa A. Rolfes , Alissa O'Halloran , Evan J. Anderson , Nancy M. Bennett , Laurie Billing , Shua Chai , Elizabeth Dufort , Rachel Herlihy , Sue Kim , Ruth Lynfield , Chelsea McMullen , Maya L. Monroe , William Schaffner , Melanie Spencer , H. Keipp Talbot , Ann Thomas , Kimberly Yousey-Hindes , Carrie Reed , and Shikha Garg Acute Cardiovascular Events Associated With Influenza in Hospitalized Adults Ami Schattner Acute Cardiovascular Events Associated With Influenza in Hospitalized Adults Eric J. Chow , Alissa O’Halloran , Melissa A. Rolfes , Carrie Reed , and Shikha Garg Metrics April 2021Volume 174, Issue 4Page: 582-583 ePublished: 20 April 2021 Issue Published: April 2021 Copyright & PermissionsCopyright © 2021 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...