The enzyme histochemistry method was used in this experiment to study the biocompatibility of the UV surface modified Dacron. The activity of the enzymes such as ALP, ACP, NADHD and LDH in the tissue surrounding both the modified and unmodified materials after a certain implantation period was semiquantitatively measured. The results showed that the biocompatibility of the surface modified Dacron was as good as that of the unmodified one.