Palladium Catalyzed Cross-Coupling Reaction of Stereodefined Cyclopropylboronic Acids with N-Heterocycl Bromides

Abstract The Suzuki-type cross-coupling reaction of stereodefined cyclopropylboronic acids with N-heterocycl bromides was investigated. In the appropriate conditions the coupling reactions readily underwent to afford stereocontrolled cyclopropyl substituted N-heterocycles in moderate to good yields The configuration of cyclopropylboronic acids retained during the reaction.