烟酰胺腺嘌呤二核苷酸
莫里斯水上航行任务
NAD+激酶
CD38
生物化学
胆碱乙酰转移酶
化学
多奈哌齐
免疫印迹
分子生物学
药理学
生物
医学
内科学
内分泌学
酶
疾病
细胞生物学
海马体
痴呆
乙酰胆碱
基因
干细胞
川地34
作者
Yiran Hu,Sanli Xing,Yan Huang,Chuan Chen,Dingzhu Shen,Jiulin Chen
标识
DOI:10.2174/1386207326666230428112358
摘要
This study shows that the new Tiaoxin Recipe can improve cognitive ability and reduce the Aβ1-42 content and senile plaque deposition in APP/PS1 mice, which may occur through the downregulation of CD38 protein expression, upregulation of SIRT3 protein expression, restoration of the NAD+ level, promotion of ATP synthesis, mitigation of energy metabolism disorders.
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