化学
硫醇
苯甲醇
功能群
醛
酒
酒精氧化
有机化学
群(周期表)
组合化学
药物化学
催化作用
聚合物
作者
Ajeet Chandra,Navin Yadav,Soumen Payra,Keshaba Nanda Parida
出处
期刊:Organic Letters
[American Chemical Society]
日期:2023-08-21
卷期号:25 (34): 6256-6261
标识
DOI:10.1021/acs.orglett.3c02017
摘要
o-Iodoxybenzoic acid (IBX) and Dess-Martin periodinane (DMP) are employed for thiol to thiosulfonate conversion at rt. DMP is better than IBX in terms of reaction rate, conversion, and required equivalents. IBX-mediated oxidation of benzyl thiols produced thiosulfonates, whereas DMP afforded O-benzyl esters. The one-pot conversion of a thiol to an ester is unprecedented; this atom-economic transformation has potential for functional group transformations (FGTs), e.g., an alcohol and an aldehyde are accessed from benzyl thiol.
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