肠道菌群
肥胖
疾病
肠道微生物群
生物
微生物群
膳食纤维
健康福利
代谢综合征
食品科学
医学
免疫学
生物信息学
内分泌学
内科学
传统医学
作者
Bryce K. Perler,Elliot S. Friedman,Gary D. Wu
出处
期刊:Annual Review of Physiology
[Annual Reviews]
日期:2023-02-10
卷期号:85 (1): 449-468
被引量:17
标识
DOI:10.1146/annurev-physiol-031522-092054
摘要
The interplay between diet, the gut microbiome, and host health is complex. Diets associated with health have many similarities: high fiber, unsaturated fatty acids, and polyphenols while being low in saturated fats, sodium, and refined carbohydrates. Over the past several decades, dietary patterns have changed significantly in Westernized nations with the increased consumption of calorically dense ultraprocessed foods low in fiber and high in saturated fats, salt, and refined carbohydrates, leading to numerous negative health consequences including obesity, metabolic syndrome, and cardiovascular disease. The gut microbiota is an environmental factor that interacts with diet and may also have an impact on health outcomes, many of which involve metabolites produced by the microbiota from dietary components that can impact the host. This review focuses on our current understanding of the complex relationship between diet, the gut microbiota, and host health, with examples of how diet can support health, increase an individual's risk for disease, and be used as a therapy for specific diseases.
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