OBJECTIVE: To conduct a statistical analysis on 371 drug-induced liver injury cases for references of clinical rational drug use and drug safety evaluation.METHODS: In this retrospective study,a total of 371 drug-induced liver injury cases were analyzed with regard to patients' sex and age,medication,manifestation of side effects,and prognosis.RESULTS: A total of 12 categories(57 kinds) of drugs were involved in the 371 drug-induced liver injury cases,leading the first three places were all anti-tuberculosis drugs.CONCLUSION: Great attention should be attached to drug-induced liver injury to prevent adverse drug reactions.