CD8型
细胞毒性T细胞
免疫学
病毒感染
病毒学
失调家庭
病毒性肝炎
肝细胞
病毒
医学
免疫系统
生物
内科学
生物化学
临床心理学
体外
作者
Miriam Bosch,Nina Kallin,SainitinDonakondaSainitin Donakonda,Ulrike Protzer,Dietmar Zehn,Dirk Wohlleber,Percy A. Knolle
出处
期刊:Zeitschrift Fur Gastroenterologie
[Thieme Medical Publishers (Germany)]
日期:2022-01-01
卷期号:60 (01): e48-e48
标识
DOI:10.1055/s-0041-1740811
摘要
Background A strong CD8 T cell response is crucial to eliminate hepatotropic viral infections such as hepatitis B virus infection. Contrastingly, a weak T cell response characterizes persistent viral infection of the liver. We aimed at pinpointing the mechanism mediating dysfunctionality in liver-resident CD8 T cells during persistent viral liver infection.
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