Rearrangement Reactions

Rearrangement reactions mostly involve breaking and/or making C—C, C—O, or C—N bonds. The migration origin is the atom from which the group moves, and the migration terminus is the atom to which it migrates. This chapter discusses the mechanism, experimental procedure, and applications of various rearrangement reactions, namely Baeyer–Villiger oxidation, Dakin oxidation, Bamberger rearrangement, Beckmann rearrangement, Benzilic Acid rearrangement, Baker–Venkataraman rearrangement, Claisen rearrangement, Eschenmoser–Claisen rearrangement, Ireland–Claisen rearrangement, and Johnson–Claisen rearrangement. They also include Overman rearrangement, Cope rearrangement, Curtius rearrangement, Demjanov rearrangement, Tiffeneau–Demjanov rearrangement, and Fries rearrangement, and Favorskii rearrangement, Fischer–Hepp rearrangement, Hofmann rearrangement, Hofmann–Martius rearrangement, Lossen rearrangement, Orton rearrangement, Pinacol–Pinacolone rearrangement, Rupe rearrangement, Schmidt rearrangement, Wagner–Meerwein rearrangement, Wolff rearrangement, Arndt–Eistert Homologation, and Zinin rearrangement.