Biomaterials and bone tissue engineering

During the last decades, bone tissue repair and regeneration have been increasing interest in the clinical therapy scientific field, and with the development of materials, biology and tissue engineering, the bone tissue engineering has been as an efficient method to treat bone defects. This review summarizes several aspects related to bone tissue engineering for bone repair and regeneration: the biomaterials in the bone tissue engineering, the stem cell behavior in bone tissue engineering, and the development of biomaterials and bone tissue engineering. We also highlight several latest advancements in bone tissue engineering. Finally, a brief summary of the bone tissue engineering challenges in the field are provided with suggestions for future research directions.