Distribution, Absorption and Excretion of 198Au-colloid and Na251CrO4 in the Chicken

In order to clarify the suitability of 198Au-colloid and Na251CrO4 as a marker of transit of the gastrointestinal content of the chicken, the distribution, absorption and excretion of 198Au-colloid and Na251CrO4 in the chicken were examined. Orally administered 198Au-colloid was not absorbed by the gastrointestinal tract and excreted into feces. Intravenously injected 198Au-colloid was not excreted into the gastrointestinal tract through the gastrointestinal wall. On the other hand, orally administered Na251CrO4 was relatively well absorbed by the gastrointestinal tract and distributed over a whole body. Intravenously injected Na251CrO4 was excreted into the gastrointestinal tract through the gastrointestinal wall and bile ducts. It seemed that 198Au-colloid was not adhered to the gastrointestinal mucosa and consequently, the transport of 198Au-colloid in the gastrointestinal tract was not delayed. It is concluded that 198Au-colloid is highly suitable as a marker of gastrointestinal transit of the chicken but Na251CrO4 is unsuitable.