Objective:To investigate the hemostatic effect of polysaccharide hemostatic particles on femoral artery bleeding in rabbits.Methods:Dissect the rabbit and isolated the left femoral artery,and cut the femoral artery.Observe the hemostatic effect of PerClotTM on it.Timing and calculate the amount of bleeding for comparing with negative control group.Results:The average amount of bleeding in PerClotTM group((1.46 ± 0.06) g on Average) less than control group((2.48±0.10)g on Average()P0.01).The average time of haemostasis in PerClotTM group((100±30.1)s on Average) less than control group((200±36.33)s on Average()P0.01).Conclusions:The hemostatic effect of polysaccharide hemostatic system is reliable.We believe that it worthy for clinical trials.