溃疡性结肠炎
多重耐药
CD19
医学
结肠炎
细胞疗法
细胞
免疫学
内科学
抗药性
生物
微生物学
抗原
疾病
遗传学
作者
Fabian Müller,Raja Atreya,Simon Völkl,Michael Aigner,Sascha Kretschmann,Soraya Kharboutli,Moritz Leppkes,Selina Sitte,Deike Strobel,Arndt Hartmann,Saurabh Mehandru,Jean–Frédéric Colombel,Georg Schett,Andréas Mackensen,Markus F. Neurath
摘要
In a patient with treatment-resistant ulcerative colitis, CD19 CAR T-cell therapy led to drug-free remission and mucosal healing, suggesting that B-cell targeting may offer a novel therapeutic pathway.
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