Tetramer based approach for efficient identification and isolation of neo-antigen specific CD8 T cells from peripheral blood (PBL) of patients with metastatic cancers
作者
Mini Bharathan,Katarina Trebska-McGowan,Anna Pasetto,Drew C. Deniger,Ken‐ichi Hanada,Jared J. Gartner,James Chih-Hsin Yang,Steven A. Rosenberg,Paul F. Robbins
Meeting abstracts Adoptive cell therapy with T cells bearing mutation specific T cell receptors (TCR) can be an effective method for treating metastatic cancers. The objective of this study was to identify mutation reactive T cells in the circulation of patients with different types of metastatic