医学
林奇综合征
结直肠癌
癌症
泌尿生殖系统
胃肠道癌
内科学
肿瘤科
家族史
妇科
作者
Leah H. Biller,Siobhan A. Creedon,Margaret R Klehm,Matthew B. Yurgelun
标识
DOI:10.1016/j.giec.2021.08.002
摘要
Lynch syndrome (LS) is a common form of inherited cancer susceptibility, which predisposes to colorectal cancer (CRC) along with a wide array of other extracolonic malignancies, including other gastrointestinal cancers, cancers of the gynecologic and genitourinary tracts, and other organ sites. Recent data have provided novel insights into patient-specific factors that can help clinicians understand an individual LS carrier's risk of extracolonic cancers, including sex, specific LS gene, age, family history of cancer, and other factors. This summary seeks to provide an update on extracolonic cancer risks in LS and provide recommendations for surveillance and risk reduction.
科研通智能强力驱动
Strongly Powered by AbleSci AI