阿替唑单抗
医学
肿瘤科
细胞毒性T细胞
内科学
癌症研究
程序性细胞死亡
肺癌
化疗
PD-L1
细胞毒性
癌症
生物
细胞凋亡
无容量
免疫疗法
体外
生物化学
作者
Leora Horn,Aaron S. Mansfield,Aleksandra Szczęsna,Libor Havel,Maciej Krzakowski,Maximilian J. Hochmair,Florian Huemer,György Losonczy,Melissa L. Johnson,Makoto Nishio,Martin Reck,Tony Mok,Sivuonthanh Lam,David S. Shames,Juan Liu,Beiying Ding,Ariel López-Chávez,Fairooz F. Kabbinavar,Wei Lin,Alan Sandler
标识
DOI:10.1056/nejmoa1809064
摘要
The addition of atezolizumab to chemotherapy in the first-line treatment of extensive-stage small-cell lung cancer resulted in significantly longer overall survival and progression-free survival than chemotherapy alone. (Funded by F. Hoffmann-La Roche/Genentech; IMpower133 ClinicalTrials.gov number, NCT02763579 .).
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