医学
前列腺癌
淋巴结
组织病理学
放射科
外科病理学
前列腺
癌症
转移
采样(信号处理)
病理
内科学
滤波器(信号处理)
计算机视觉
计算机科学
作者
Melline G.M. Schilham,Heidi V.N. Küsters‐Vandevelde,Diederik M. Somford,Mark Rijpkema,Martin Gotthardt
出处
期刊:Clinical Nuclear Medicine
[Ovid Technologies (Wolters Kluwer)]
日期:2022-04-19
卷期号:47 (6): 559-561
被引量:3
标识
DOI:10.1097/rlu.0000000000004158
摘要
Abstract Detection of lymph node (LN) metastases in prostate cancer (PCa) is pivotal for accurate staging and determining treatment options. To date, the reference standard for nodal staging is histopathological examination of all harvested surgical specimens from extended pelvic LN dissections. However, this is a labor-intensive process, and small metastatic foci can be missed due to sampling effects. With current research expanding toward using radiolabeled prostate-specific membrane antigen ligands for image-guided surgery, new opportunities arise for image-guided pathological assessment of surgical specimens. Here, we illustrate how molecular imaging can complement histopathology and improve accurate detection of LN metastases.
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