Microstructure of tooth enamel prism-like fluoridated hydroxyapatite regenerated on enamel surface

Objective: To construct fluoridated hydroxyapatite(FA) enamel prism-like structure on the natural enamel surface of human teeth by a simple chemical approach.Methods: FA enamel prism-like structure with different sizes and shapes were produced on the enamel surface of human teeth by a chemical approach using EDTA-Ca-Na2,NaH2PO4·H2O and NaF as the reactants.The physicochemical and biological properties of the enamel-like material were studied by SEM,XRD,FTIR,XPS,MTT assay and bacterial inhibition ring test.Results: The compacted well-aligned FA crystals were produced,which could grow directly on the enamel surface.The nanorods of the crystal were approximately 6 μm in length and 300 nm in diameter whose physicochemical property and biological performance were similar to those of natural enamel.The enamel-like material showed biocompatibility and certain bacteriostasis.Conclusion: The FA product may simulate the structure,component and decay resistance of human tooth enamel.