Optimization of Extract Technology of Corydalis decumbens by Orthogonal Experiment

Objective:To optimize extraction process of Corydalis decumbens.Method:The content of bicuculline,protopine,tetrahydropalmatine,palmatine and yield of extract as indexes,optimization of extract technology by orthogonal experiment and correlation test and comprehensive balance method.Result:Optimum extraction condition was as follows:refluxing extracted 3 times with 11 times the amount of 70% ethanol by 2.5 h each time.Conclusion:This optimum technology was stable and feasible,it could keep effective components better.