多糖
益生元
食品科学
DPPH
化学
果糖
半乳糖
发酵
甘露糖
肠道菌群
抗氧化剂
生物化学
作者
Athira Jayasree Subhash,Gafar Babatunde Bamigbade,Mohammad Tarique,Basel K. al-Ramadi,Basim Abu-Jdayil,Afaf Kamal‐Eldin,Laura Nyström,Mutamed Ayyash
标识
DOI:10.1016/j.fochx.2024.101354
摘要
Polysaccharides are abundant macromolecules. The study extracted date seed polysaccharides (UPS) using ultrasound-assisted deep eutectic solvent extraction to valorize date seeds. UPS were subjected to comprehensive characterization and evaluation of their bioactivity, prebiotic properties, and their potential to modulate the gut microbiome. Characterization revealed UPS's heteropolysaccharide composition with galactose, mannose, fructose, glucose, and galacturonic acid respectively in 66.1, 13.3, 9.9, 5.4, and 5.1%. UPS showed a concentration-dependent increase of radical scavenging and antioxidant activities, evidenced by FRAP, TAC, and RP assays. They also displayed antimicrobial efficacy against E. coli O157:H7, S. typhimurium, S. aureus, and L. monocytogenes. Rheological analysis showed UPS's elastic-dominant nature with thixotropic tendencies. UPS inhibited α-glycosidase, α-amylase, and ACE up to 86%, and reduced Caco-2 and MCF-7 cell viability by 70% and 46%, respectively. UPS favored beneficial gut microbiota growth, releasing significant SCFAs during fecal fermentation.
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