Long-Chain Fatty Acid Redistribution Induced by SLC27A2 Deficiency Facilitates Hypoxic Adaptation and Immunosuppression in Hepatocellular Carcinoma

SLC27A2 downregulation in response to environmental stressors limits fatty acid uptake to mitigate lipid peroxidation in hepatocellular carcinoma, providing potential opportunities for precision treatment and calling for caution with fatty acid-targeted therapies.