The efficacy and safety of cefovecin in the treatment of feline abscesses and infected wounds

医学 阿莫西林 克拉维酸 阿莫西林/克拉维酸 外科 内科学 抗生素 生物 微生物学
作者
Michael Stegemann,J. Sherington,C. A. Passmore
出处
期刊:Journal of Small Animal Practice [Wiley]
卷期号:48 (12): 683-689 被引量:16
标识
DOI:10.1111/j.1748-5827.2007.00390.x
摘要

O bjectives : To determine the efficacy and safety of cefovecin for the treatment of bacterial abscesses and wounds in cats at clinics in Germany, France, Spain and the UK. M ethod : Cats with abscesses or wounds were enrolled. Cats (217) were randomised to treatment with either cefovecin administered by subcutaneous injection at 14 day intervals or amoxicillin/clavulanic acid as twice‐daily oral tablets for 14 days. Treatment courses were repeated at 14 day intervals, when deemed necessary. Clinicians assessing lesions were masked to treatment allocation. Only animals with a confirmed pretreatment bacterial pathogen were included in the efficacy analysis. Cases were evaluated 28 days after initiation of the final course of treatment. R esults : Cefovecin was as efficacious as amoxicillin/clavulanic acid, and efficacy was 100 per cent for both treatments. C linical s ignificance : Cefovecin, administered as a single subcutaneous injection repeated at 14 day intervals as required, was shown to be as efficacious as oral amoxicillin/clavulanic acid in the treatment of abscesses/wounds in cats.
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