明胶
人的心脏
嵌入
脚手架
生物医学工程
纳米技术
高分辨率
分辨率(逻辑)
材料科学
组织工程
化学
计算机科学
3D打印
工程类
复合材料
生物化学
人工智能
医学
内科学
遥感
地质学
作者
Andrew Lee,Andrew R. Hudson,Daniel J. Shiwarski,Joshua W. Tashman,Thomas J. Hinton,Saigopalakrishna S. Yerneni,Jacqueline M. Bliley,Phil G. Campbell,Adam W. Feinberg
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:2019-08-02
卷期号:365 (6452): 482-487
被引量:1116
标识
DOI:10.1126/science.aav9051
摘要
If I only had a heart 3D bioprinting is still a fairly new technique that has been limited in terms of resolution and by the materials that can be printed. Lee et al. describe a 3D printing technique to build complex collagen scaffolds for engineering biological tissues (see the Perspective by Dasgupta and Black). Collagen gelation was controlled by modulation of pH and could provide up to 10-micrometer resolution on printing. Cells could be embedded in the collagen or pores could be introduced into the scaffold via embedding of gelatin spheres. The authors demonstrated successful 3D printing of five components of the human heart spanning capillary to full-organ scale, which they validated for tissue and organ function. Science , this issue p. 482 ; see also p. 446
科研通智能强力驱动
Strongly Powered by AbleSci AI