萧条(经济学)
作用机理
血清素
精神科
多巴胺
再摄取抑制剂
再摄取
神经科学
去甲肾上腺素
心理学
机制(生物学)
心理治疗师
医学
受体
内科学
生物
哲学
宏观经济学
经济
认识论
体外
生物化学
标识
DOI:10.4088/jcp.13097tx3c
摘要
Article AbstractAntidepressants, such as selective serotonin reuptake inhibitors (SSRIs), may alleviate depressive symptoms but also leave residual symptoms. The mechanism of action of SSRIs increases serotonin (5-HT) activity but decreases norepinephrine (NE) and dopamine (DA) activity. By engaging additional targets (eg, NE, DA) along with 5-HT, clinicians may help patients with residual symptoms and treatment-resistant depression. Dual-acting agents and combination strategies can be used to target specific symptoms or block/activate specific receptors for broader therapeutic benefits. Clinicians who understand the mechanism of action of antidepressants can switch or combine agents as needed to help patients achieve complete remission. This CME activity is expired. For more CME activities, visit cme.psychiatrist.com. Find more articles on this and other psychiatry and CNS topics: The Journal of Clinical Psychiatry The Primary Care Companion for CNS Disorders
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