医学
肺移植
肺
钙调神经磷酸酶
移植
肺功能
重症监护医学
外科
内科学
作者
Laurent Godinas,Dirk Van Raemdonck,Laurens J. Ceulemans,Robin Vos,Geert M. Verleden
出处
期刊:Journal of Thoracic Disease
[AME Publishing Company]
日期:2019-11-01
卷期号:11 (11): E200-E203
被引量:4
标识
DOI:10.21037/jtd.2019.11.02
摘要
Lung transplantation is a recognized treatment for end-stage lung disease for selected patients for whom no other options are available (1). Since the introduction of calcineurin inhibitors in the 1980’s, lung transplantation became a reasonable treatment with improved outcomes (2). However, chronic rejection or chronic lung allograft dysfunction (CLAD) remains the major limitation for long-term survival (3,4), accounting for more than 40% of deaths beyond the first year after pulmonary transplantation (4). CLAD leads to a progressive and irreversible loss of function of the transplanted organ.
科研通智能强力驱动
Strongly Powered by AbleSci AI