炎症
冠状动脉疾病
C反应蛋白
全身炎症
动脉
生物标志物
作者
Mehmet Ozgur Erdogan,Mehmet Akif Erdöl,Selcuk Ozturk,Tahir Durmaz
出处
期刊:Biomarkers in Medicine
[Future Medicine]
日期:2020-11-12
卷期号:14 (16): 1553-1561
被引量:14
标识
DOI:10.2217/bmm-2020-0274
摘要
Aim: The study aimed to investigate and compare the predictive capacity of a systemic immune-inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) to determine a hemodynamically significant coronary artery stenosis assessed by fractional flow reserve (FFR). Patients & methods: A total of 207 chronic coronary syndrome patients with FFR measurement were enrolled in the study. NLR, PLR and SII levels were calculated. Results: The cut-off value of the SII (620) was associated with 78.4% sensitivity and 64.0% specificity to predict a hemodynamically significant stenosis. SII level independently predicted FFR ≤0.80. Conclusion: SII is an independent predictor of functionally significant coronary stenosis detected by FFR in chronic coronary syndrome patients. SII levels can predict hemodynamically severe obstruction better than NLR and PLR.
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