[Surgical treatment for inflammatory myofibroblastic tumor in genito-urinary system: a study of 15 cases].

Objective: To present 15 cases of inflammatory myofibroblastic tumor (IMT) in genitor-urinary system, and analyze the characteristics, diagnosis and treatment of the disease. Methods: The diagnostic and therapeutic process of 15 confirmed cases admitted to Sun Yat-sen University Cancer Center between March 2009 and September 2017 were retrospectively analyzed. Of the total cases, 11 cases were diagnosed with cystic IMT with a maximum diameter of 1.0-4.5 cm, 8 cases underwent transurethral resection of bladder tumor(TURBT)and 4 of them underwent partial cystectomy after TURBT and 3 underwent partial cystectomy directly. Two cases were renal IMT with a maximum diameter of 4.0-9.0 cm, one underwent partial nephrectomy and the other accepted radical nephrectomy. One case who was diagnosed with prostatic IMT with a maximum diameter of 3.4 cm underwent transurethral resection of the prostate (TURP) and postoperative radiotherapy. One case who was diagnosed with perineal IMT with a maximum diameter of 2.1 cm underwent tumor resection. Results: The patients were followed up for 10-32 months with a median time of 27 months. No cases relapsed during the follow-up. Conclusion: Surgery is the preferred method for treating IMT in genitor-urinary system. Retrospective study shows a good prognosis in IMT patients, but a long-term follow-up is still required.目的： 探讨发生于泌尿生殖系统炎性肌纤维母细胞瘤（IMT）的临床特点与诊治方法。 方法： 回顾性分析中山大学附属肿瘤医院2009年3月至2017年9月收治15例发生于泌尿生殖系统IMT、并且接受外科治疗的临床资料。其中男5例，女10例；年龄20~76岁，平均47岁；其中膀胱IMT 11例，肿瘤最大直径1.0~4.5 cm；经尿道膀胱肿瘤电切术8例，其中4例经尿道膀胱肿瘤电切术后行膀胱部分切除；直接行膀胱部分切除术3例；肾脏IMT 2例，肿瘤最大直径4.0~9.0 cm；肾部分切除术1例，肾切除术1例；前列腺IMT 1例，行经尿道前列腺电切术，肿瘤较大，术后复查提示肿瘤残留，行术后放疗；外阴IMT 1例，行手术切除。 结果： 随访10~32个月，平均27个月，膀胱肿瘤术后无复发；肾脏IMT手术治疗2例均无复发；前列腺IMT术后行辅助放疗、外阴IMT术后随访均无复发。 结论： 泌尿生殖系统炎性肌纤维母细胞瘤临床少见，治疗以手术切除为主，手术尽量将肿瘤连续完整切除以及尽可能保留器官功能。虽然预后良好，仍需要长期随访。.