药物输送
纳米技术
微乳液
材料科学
输送系统
自愈水凝胶
计算机科学
生物医学工程
医学
化学
肺表面活性物质
生物化学
高分子化学
作者
Vandana Patravale,Abhijit A. Date,Rishikesh M. Kulkarni
标识
DOI:10.1211/0022357023691
摘要
Nanosuspensions have emerged as a promising strategy for the efficient delivery of hydrophobic drugs because of their versatile features and unique advantages. Techniques such as media milling and high-pressure homogenization have been used commercially for producing nanosuspensions. Recently, the engineering of nanosuspensions employing emulsions and microemulsions as templates has been addressed in the literature. The unique features of nanosuspensions have enabled their use in various dosage forms, including specialized delivery systems such as mucoadhesive hydrogels. Rapid strides have been made in the delivery of nanosuspensions by parenteral, peroral, ocular and pulmonary routes. Currently, efforts are being directed to extending their applications in site-specific drug delivery.
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