上睑下垂
软骨细胞
炎症体
软骨
骨关节炎
阿格里坎
肿瘤坏死因子α
细胞生物学
炎症
医学
免疫学
病理
化学
生物
解剖
关节软骨
替代医学
作者
Hao Tang,Xiaoshan Gong,Jingjin Dai,Jun Gu,Zicai Dong,Yuan Xu,Zhaoyang Hu,Chunrong Zhao,Jiezhong Deng,Shiwu Dong
标识
DOI:10.1016/j.jot.2023.11.005
摘要
This study underscores the significance of the IRF1/GBP5 axis in NLRP3 inflammasome-mediated chondrocyte pyroptosis and osteoarthritic chondrocyte injury. Modulating IRF1 and GBP5 expression could serve as a novel therapeutic target for OA.
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