siRNA modification and delivery for drug development

Common chemical modifications used in small interfering RNA (siRNA) therapeutics Correction to: siRNA modification and delivery for drug development: (Trends in Molecular Medicine, 28:10 p:892–893, 2022)Zhang et al.Trends in Molecular MedicineOctober 12, 2022In BriefIn the original version of Figure 2, we showed some examples of chemical modification designs. In order to provide more accurate information, we changed several 2′-O-methyl (2′-OMe) modification sites with 2′-deoxy-2′-fluoro (2′-F) in the second example in Figure 2. We also slightly modified the chemical structures of inverted abasic deoxyribonucleotide (invAb). We apologize for any confusion this caused. Full-Text PDF