化学
双功能
部分
反应性(心理学)
联氨(抗抑郁剂)
亲核取代
亲核细胞
纤维素
多糖
水合物
结合
化学改性
组合化学
有机化学
高分子化学
催化作用
色谱法
医学
数学分析
替代医学
数学
病理
作者
Katja Geitel,Hendryk Würfel,Wolfgang Günther,Thomas Heinze
标识
DOI:10.1016/j.carbpol.2023.121727
摘要
A simple synthesis of amino polysaccharides (PS) could be developed. Phenyl carbonates (PC) of xylan, dextran, and cellulose were easily transferred into PS carbazates by conversion with hydrazine hydrate. The degree of substitution could be adjusted by varying the molar ratio of hydrazine to PS repeating unit, enabling the preparation of both pure PS carbazates and derivatives with bifunctional reactivity containing the reactive PC and the amino group of the carbazate moiety. Further functionalization of the derivatives is feasible with carbonyl compounds like aldehydes at the carbazate groups. The reactivity of carbazate groups is shown by the reaction with 4-fluorobenzaldehyde, resulting in the formation of Schiff base conjugates.
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