In this work, the protozoan of Toxoplasma gondii (Nicolle & Manceaux, 1908)(Apicomplexa:Sarcocystidae) is reviewed. Toxoplasma gondii is intracellular parasite belonging to thephylum of apicomplexa. It is a common protozoan of warm-blooded animals, and it distributesworldwide, causing infection in eyes’ retina, brain and other regions of the body. It has been reported thattoxoplasmosis is one of neglected disease by CDC. The first discovery of this intracellular parasite was in1908, and later in 1957 was detected causing abortion in animal. In 1970, it was the first time forrecognizing the life cycle of it, they were found that cats (felids in general) are the final host, and thestage of oocyst is occurring in the stool of infected cats. For prevention, T.gondii can be prevented byhygiene, and it considers the only way preventive measure because vaccination technology is notdiscovered yet for toxoplasmosis prevention in human.