血小板
血小板活化
血栓
致密颗粒
下调和上调
内分泌学
内科学
受体
医学
化学
药理学
细胞生物学
生物
生物化学
基因
作者
Wenhua Liu,Gaoxiang Li,Jianfeng Shi,Yu Gao,Peiliang Fang,Yichao Zhao,Fangyuan Zhong,Xiao Hua Guo,Yuyan Lyu,Xingwen Da,Zhaoyan Li,Jingjing Fa,Liuhua Hu,Ancai Yuan,Lei Chen,Junling Liu,Alex F. Chen,Bin Sheng,Yong Ji,Xiyuan Lu
标识
DOI：10.1161/circresaha.124.325645
摘要
We provide the first evidence that nuclear receptor NR4A1 negatively regulates platelet activation and thrombus formation. NR4A1 may serve as a novel therapeutic target for managing thrombosis-based cardiovascular diseases, especially with hypercholesterolemia.
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(2025-6-4)
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