亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Association between cardiovascular risk factors and the occurrence of giant cell arteritis: a systematic review and meta-analysis

医学 荟萃分析 优势比 超重 2型糖尿病 内科学 置信区间 观察研究 糖尿病 流行病学 肥胖 队列研究 疾病 内分泌学
作者
F. Barde,L. Pacoureau,Alexis Elbaz,Raphaèle Séror,Yann Nguyen
出处
期刊:Rheumatology [Oxford University Press]
标识
DOI:10.1093/rheumatology/keaf164
摘要

Abstract Objectives We aimed to analyze the association between cardiovascular risks factors and the onset of giant cell arteritis (GCA) through a systematic review and meta-analysis of observational studies. Methods Three databases (MEDLINE, EMBASE, WEB OF SCIENCE) were systematically reviewed. Epidemiological studies on the association between six cardiovascular risk factors (type 2 diabetes, hypertension, dyslipidaemia, smoking, overweight/obesity, history of a cardiovascular disease) and the risk of GCA were eligible. Risk of bias was assessed using the ROBINS-E scale. Pooled associations for studies assessing the same outcome were reported as odds ratios (OR) and their 95% confidence interval (CI). Results The search strategy identified 4,210 references, of which 43 studies were analyzed and 17 were included in the meta-analysis (11 case-control studies, four cohort studies). An inverse association was found between type 2 diabetes and risk of GCA (OR = 0.75, 95% CI 0.61–0.93) and whereas history of cardiovascular disease was positively associated with GCA with risk (OR = 1.28, 95% CI 1.18–1.38). We found a trend towards a decreased risk of GCA in overweight participants (OR 0.64; 95% CI 0.41–1.00). Conclusion Our study showed an inverse association of type 2 diabetes and a positive association of a history of cardiovascular disease with GCA risk. There is also a trend towards an inverse association with overweight. The pathophysiological mechanisms underlying these findings may involve an effect of cardiovascular risk factors themselves, a condition underlying these factors such as diet, or a condition following their diagnosis such as their treatment.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
科研通AI6应助闪闪飞机采纳,获得10
6秒前
chloe完成签到,获得积分10
8秒前
33发布了新的文献求助10
9秒前
15秒前
王娅楠完成签到,获得积分10
17秒前
17秒前
王娅楠发布了新的文献求助10
20秒前
jiayu123发布了新的文献求助10
20秒前
jiayu123完成签到,获得积分20
26秒前
李健应助王娅楠采纳,获得10
30秒前
45秒前
33发布了新的文献求助10
51秒前
jyy应助科研通管家采纳,获得10
1分钟前
JamesPei应助Yike采纳,获得10
1分钟前
33发布了新的文献求助10
1分钟前
送人头完成签到,获得积分10
2分钟前
闪闪飞机完成签到,获得积分10
2分钟前
过时的手套完成签到,获得积分10
2分钟前
科研通AI6应助过时的手套采纳,获得10
2分钟前
赘婿应助冰冰采纳,获得10
2分钟前
彩虹儿应助33采纳,获得10
2分钟前
邢夏之完成签到 ,获得积分10
3分钟前
唐泽雪穗完成签到,获得积分10
3分钟前
jyy应助科研通管家采纳,获得10
3分钟前
jyy应助科研通管家采纳,获得10
3分钟前
量子星尘发布了新的文献求助10
4分钟前
5分钟前
彩虹儿应助诚心山灵采纳,获得10
6分钟前
彩虹儿应助诚心山灵采纳,获得10
6分钟前
fufufu123完成签到 ,获得积分10
6分钟前
机智的孤兰完成签到 ,获得积分10
6分钟前
冰冰发布了新的文献求助10
6分钟前
Survivor完成签到,获得积分10
7分钟前
lovelife完成签到,获得积分10
8分钟前
cqhecq完成签到,获得积分10
9分钟前
cherry完成签到,获得积分10
9分钟前
Kevin完成签到,获得积分10
9分钟前
cherry发布了新的文献求助10
10分钟前
我是老大应助33采纳,获得10
11分钟前
12分钟前
高分求助中
(应助此贴封号)【重要!!请各用户(尤其是新用户)详细阅读】【科研通的精品贴汇总】 10000
二维材料在应力作用下的力学行为和层间耦合特性研究 600
苯丙氨酸解氨酶的祖先序列重建及其催化性能 500
Schifanoia : notizie dell'istituto di studi rinascimentali di Ferrara : 66/67, 1/2, 2024 470
Effects of different anesthesia methods on bleeding and prognosis in endoscopic sinus surgery: a meta-analysis and systematic review of randomized controlled trials 400
Laboratory Animal Technician TRAINING MANUAL WORKBOOK 2012 edtion 400
Progress and Regression 400
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 内科学 生物化学 物理 计算机科学 纳米技术 遗传学 基因 复合材料 化学工程 物理化学 病理 催化作用 免疫学 量子力学
热门帖子
关注 科研通微信公众号,转发送积分 4844734
求助须知:如何正确求助?哪些是违规求助? 4144938
关于积分的说明 12833849
捐赠科研通 3891632
什么是DOI,文献DOI怎么找? 2139250
邀请新用户注册赠送积分活动 1159267
关于科研通互助平台的介绍 1059558