环加成
区域选择性
羟甲基
催化作用
钯
化学
组合化学
立体化学
有机化学
作者
Anaïs Scuiller,Xueyang Liu,Marie Cordier,Julian Garrec,Alexis Archambeau
出处
期刊:Synlett
[Georg Thieme Verlag KG]
日期:2021-05-19
卷期号:32 (10): 981-986
被引量:8
标识
DOI:10.1055/s-0040-1706038
摘要
Abstract A Pd-catalyzed oxa-(4+4)-cycloaddition between 1-azadienes and (2-hydroxymethyl)allyl carbonates is described. Aurone-derived azadienes furnished polycyclic 1,5-oxazocines in good yields. Interestingly, linear azadienes have also been involved and yielded monocyclic heterocycles with complete regioselectivity. DFT calculations were carried out to gain insight on this observation.
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