医学
神经纤维层
青光眼
眼科
视网膜
视神经
神经节
光学相干层析成像
内丛状层
验光服务
解剖
作者
Gregg D Miller,Omar Abu-Qamar,Sarwat Salim
出处
期刊:Journal of Glaucoma
[Ovid Technologies (Wolters Kluwer)]
日期:2021-03-17
卷期号:30 (5): e213-e221
被引量:6
标识
DOI:10.1097/ijg.0000000000001834
摘要
Précis: Myopic glaucoma suspects, particularly with high myopia, experience thinning of nontemporal parameters of retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer (GCIPL), without change in optic nerve head (ONH) parameters. Purpose: The aim was to assess the effect of myopia on RNFL, GCIPL, and ONH parameters in glaucoma suspects. Materials and Methods: Seventy-six eyes of glaucoma suspects studied with Cirrus high definition optical coherence tomography were divided into low (n=27), moderate (n=25), and high myopia (n=24) groups. Optical coherence tomography parameters were correlated with spherical equivalent (SE) and evaluated with areas under the receiver operating characteristic curve for quantifying diagnostic ability to differentiate high myopia from nonhigh myopia. Results: In high myopia, SE was positively correlated with thinning of average, minimum, and nontemporal GCIPL and thinning of average and nontemporal RNFL (P<0.05 for all), but not for inferior RNFL (P=0.28). In moderate myopia, SE was correlated with thinning of inferonasal and minimum GCIPL as well as superior and inferior RNFL (P<0.05 for all). SE was not correlated with ONH parameters in moderate or high myopia (P>0.05). The largest areas under the receiver operating characteristic curve for RNFL and GCIPL parameters were for superior (0.82) and superonasal (0.80) regions, respectively, with comparable diagnostic ability (P=0.74). Conclusion: High myopia, in particular, is associated with thinning of average RNFL, average and minimum GCIPL, and nontemporal parameters of both RNFL and GCIPL, warranting consideration of refractive status in glaucoma suspects.
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