The diagnostic value of quantitative determination of myocardial troponin I on acute myocardial infarction

Objective:To observe the dynamic changes of serum myocardial troponin I(cTnI) in patients with acute myocardial infarction(AMI).Methods:Blood samples were respectively obtained at admission 6,12,48 hours and 10 days later from 19 patients with acute myocardial infarction and those in 118 normal subjects served as controll group.With ELISA method,the serum concentrations cTnI in the two groups were simulataneously measured by ∑960 apparatus and compared with CK-MB.Results:The rising time of serum cTnI in AMI was earlier and its duration was longer.It was superior to CK-MB in veracity,sensitivity and specificity for diagnosic of myocardial damage.Conclusion:The present study suggests that quantitative determination of serum cTnI has very important clinical value on diagnosis of acute myocardial infarction.