【Objective】To investigate the relationship between liver regeneration and pancreas regeneration in rats.【Method】 20 SD rats were randomized into 4 groups:Establish 15 male SD rats model of liver regeneration by 58% hepatectomy.Control group5 SD rats only to switch abdominal operation.After 2 weeks,observe the phenomenon of the liver regeneration and pancreas regeneration by immunolhistochemistry,the regeneration phenomenon is not observed in control group.【Result】Liver and pancreas have different levels of regeneration phenomenon in experimental group.【Conclusion】 When the liver in the regeneration of active cases,the inducing factor will also cause regeneration of the pancreas