质谱法
化学
干涉测量
计算生物学
色谱法
物理
生物
光学
作者
Vincent Jung,Kévin Roger,Cérina Chhuon,Louise Pannetier,Joanna Lipecka,Josué Sulub Gomez,Pascal Chappert,Alain Charbit,Chiara Guerrera
出处
期刊:Proteomics
[Wiley]
日期:2022-01-05
卷期号:22 (9)
被引量:3
标识
DOI:10.1002/pmic.202100031
摘要
Biolayer interferometry (BLI) is a technology which allows to study the affinity between two interacting macro-molecules and to visualize their kinetic of interaction in real time. In this work, we combine BLI interaction measurement with mass spectrometry in order to identify the proteins interacting with the bait. We provide for the first time the proof of concept of the feasibility of BLI-MS in complex biological mixtures.
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