Effects of Tai Chi Versus General Aerobic Exercise on Depressive Symptoms and Serum Lipid Levels Among Older Persons With Depressive Symptoms: A Randomized Controlled Study

Tai Chi, a mindfulness-based aerobic exercise, may alleviate depressive symptoms and improve physiological markers in older adults. However, its distinct effects compared with general aerobic exercise remain unclear. To compare the effects of Tai Chi and general aerobic exercise on depressive symptoms and serum lipid levels in community-dwelling older adults with mild to moderate depression, a randomized controlled trial was conducted. Participants were randomly assigned to Tai Chi ( n = 120) or general aerobic exercise ( n = 120) for 3 months. Depressive symptoms and serum lipid levels were measured at baseline and postintervention. A generalized estimating equation was used to assess group differences over time. The Tai Chi group exhibited significantly greater reductions in depressive symptoms and improvements in serum lipid profiles compared with the general aerobic exercise group. Tai Chi’s mind–body synergy may enhance its antidepressant effects, offering a promising approach to mental health and healthy aging.