审查(临床试验)
统计
比例危险模型
计量经济学
估计
队列
置信区间
数学
计算机科学
工程类
系统工程
作者
Yuqing Ma,Peijie Wang,Yichen Lou,Jianguo Sun,Alzheimer's Disease Neuroimaging Initiative
摘要
Abstract The additive hazards model is one of the most commonly used models for regression analysis of failure time data, and many methods have been developed for its estimation. In this article, we consider the situation where one observes informatively interval‐censored data arising from case‐cohort studies where covariate information is collected only for a small subcohort of study subjects. By informative or dependent censoring, we mean that the failure time of interest and the censoring mechanism may be correlated. For estimation, we will develop a sieve inverse probability weighting estimation procedure with the use of Bernstein polynomials. The resulting estimators of regression parameters are shown to be consistent and asymptotically normal. An extensive simulation study is conducted and suggests that the proposed method works well in practical situations. An example is also provided.
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