In common with most physicians who use hypodermic medication extensively, I have for some time been dissatisfied with the ordinary hypodermic syringe. Asepsis is uncertain, the making of the solution is time-consuming, and impossible where water is not available; the joints often leak; the piston occasionally sticks, and the needle becomes dull and rusty from boiling. I wished a syringe that could be used instantly, that was sterile, that contained within itself the desired drug in permanent solution. I have, therefore, devised the following instrument which has replaced, in my practice and in that of a few conferes, the time-honored piston syringe, with detachable needle and accompanying assortment of tablets. The cannula is permanently attached to the closed end of the collapsible tube. The tube itself is of pure tin, of extremely thin walls, and so constructed that the entire contents may be expressed, when closed, at the folded end,