Simplification of Spectra for the Determination of Coupling Constants from Homonuclear Correlated 2D NMR Spectra

Without additional measurements having to be made, coupling constants can be determined from H,H‐COSY spectra using the DISCO (Difference and Sums in COSY spectra) method. The structure elucidation of compounds with complicated 1H‐NMR spectra, e.g., natural products, is thereby facilitated.