Distribution, functionality and gene regulation of folate receptor isoforms: implications in targeted therapy

药物输送 癌症治疗 抗药性 分布(数学) 放射治疗 药品 靶向给药 癌症治疗 纳米技术 靶向治疗 生物 药理学 医学 风险分析(工程) 内科学 外科 癌症 材料科学 数学 数学分析 微生物学
作者
Hala Elnakat
出处
期刊:Advanced Drug Delivery Reviews [Elsevier BV]
卷期号:56 (8): 1067-1084 被引量:643
标识
DOI:10.1016/j.addr.2004.01.001
摘要

Today, in diverse medical and clinical fields, including cancer treatment, nanoscience has evolved and evolved. Cancer and its forms, on the other hand, have been rumored and inclusive, and many individuals suffer from this fatal and lethal condition. Actually, even with the medicinal effect, current therapeutic approaches, including chemotherapy, radiotherapy, etc., create symptoms that are inconvenient for patients. Scientists and scholars are also working to establish and, strengthen the options and methods of therapy to deal with this dangerous illness. Nanoscience and nanotechnology have been popular today, their different areas, including nanoparticles, are commonly used for a number of applications, especially for drug delivery and diagnostic products, and cases of imaging. Release mechanisms focused on nanotechnology have a profound effect on the release of cancer drugs. Biomaterials and bio-engineering developments are leading to novel approaches to nanoparticles that could offer a new way for cancer patients to improve. In the drug release method, Nano-technology has had a great effect on the selection of cancer cells, the release of a targeted drug, and the overcoming of traditional chemotherapy limitations. This article discusses the drug delivery to tumor tissue, a method that is more effective than traditional drug delivery methods, also many new nanoparticles have solved the problem of cell resistance to the drug, provided a new field in the treatment of cancer.
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