Optic Nerve in Multiple Sclerosis Diagnostic Criteria

Multiple sclerosis (MS) diagnostic criteria were revised in 2017 to allow inclusion of symptomatic supratentorial, infratentorial, and spinal cord lesions in MRI criteria for dissemination in space and time.1 This recommendation was based on new evidence that including symptomatic lesions improves the performance of MS diagnostic criteria in patients with clinically isolated syndromes (CIS) affecting the brainstem or spinal cord.2 Inclusion of symptomatic brain and spinal cord lesions streamlines the diagnostic process in people with suspected MS, facilitating earlier diagnosis and treatment decisions.3