Relation between Gut Microbiota and Cancer

Human has about 100 trillion symbiotic microbes in the gut with 300-1000 different species. Gut microbiota is associated with host metabolism, obesity, diabetes, hepatic disorder, and cancer. Nowadays, studies are focusing on the role of gut microbiota in cancer. Evidence shows that Fusobacterium is associated with colorectal cancer when its genome was confirmed by 16SRNA analysis and PCR technique in cancerous cell. The complete mechanism of gut microbe involvement in cancer is still unknown. There may be some association of toxic metabolites of gut microbes, dietary substances, and the immune response. This review will help to attain the brief knowledge about the research till now in the regard of gut microbiota with cancer. The study will also reveal the research of using gut microbes for anticancer therapy. It is examined that Lactobacillus rhamnosus in the form of probiotics has a significant role in anticancer therapy. The anticancerous therapeutic and immunogenic role of gut microbiota must be further studied.